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1

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

Zou, W., Wolchok, J. D., Chen, L.

Journal:

Science Translational Medicine

Year:

2016

Language:

english

File:

PDF, 918 KB

english, 2016

2

The role of surgery in the management of gestational trophoblastic disease

W.B. Jones, J. Wolchok, J.L. Lewis Jr

Journal:

International Journal of Gynecological Cancer

Year:

1996

Language:

english

File:

PDF, 543 KB

english, 1996

3

Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial

Robert, Caroline, Ribas, Antoni, Wolchok, Jedd D, Hodi, F Stephen, Hamid, Omid, Kefford, Richard, Weber, Jeffrey S, Joshua, Anthony M, Hwu, Wen-Jen, Gangadhar, Tara C, Patnaik, Amita, Dronca, Roxana,

Journal:

Year:

2014

Language:

english

File:

PDF, 364 KB

english, 2014

4

Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial

Eggermont, Alexander M M, Chiarion-Sileni, Vanna, Grob, Jean-Jacques, Dummer, Reinhard, Wolchok, Jedd D, Schmidt, Henrik, Hamid, Omid, Robert, Caroline, Ascierto, Paolo A, Richards, Jon M, Lebbé, Céle

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

5

Cancer immunotherapy using checkpoint blockade

Ribas, Antoni, Wolchok, Jedd D.

Journal:

Year:

2018

Language:

english

File:

PDF, 668 KB

english, 2018

6

Putting the Immunologic Brakes on Cancer

Journal:

Year:

2018

Language:

english

File:

PDF, 490 KB

english, 2018

7

Anti–CTLA-4 Antibody Therapy: Immune Monitoring During Clinical Development of a Novel Immunotherapy

Margaret K. Callahan, Jedd D. Wolchok, James P. Allison

Journal:

Seminars in Oncology

Year:

2010

Language:

english

File:

PDF, 693 KB

english, 2010

8

The role of lipopolysaccharide in T-cell responses following DNA vaccination

William G. Hawkins, Jiri Trcka, Neil Segal, Nathalie E. Blachere, Jason S. Gold, Yoichi Moroi, Wilbur B. Bowne, Jonathan J. Lewis, Jedd D. Wolchok, Alan N. Houghton

Journal:

Year:

2003

Language:

english

File:

PDF, 113 KB

english, 2003

9

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

Hamid, Omid, Robert, Caroline, Daud, Adil, Hodi, F. Stephen, Hwu, Wen-Jen, Kefford, Richard, Wolchok, Jedd D., Hersey, Peter, Joseph, Richard W., Weber, Jeffrey S., Dronca, Roxana, Gangadhar, Tara C.,

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 701 KB

english, 2013

10

Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma

Wolchok, Jedd D., Hodi, F. Stephen, Weber, Jeffrey S., Allison, James P., Urba, Walter J., Robert, Caroline, O'Day, Steven J., Hoos, Axel, Humphrey, Rachel, Berman, David M., Lonberg, Nils, Korman, Al

Journal:

Annals of the New York Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 733 KB

english, 2013

11

Nivolumab plus Ipilimumab in Advanced Melanoma

Wolchok, Jedd D., Kluger, Harriet, Callahan, Margaret K., Postow, Michael A., Rizvi, Naiyer A., Lesokhin, Alexander M., Segal, Neil H., Ariyan, Charlotte E., Gordon, Ruth-Ann, Reed, Kathleen, Burke, M

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 646 KB

english, 2013

12

Combination Therapy with Anti-CTLA-4 and Anti-PD-1 Leads to Distinct Immunologic Changes In Vivo

Das, R., Verma, R., Sznol, M., Boddupalli, C. S., Gettinger, S. N., Kluger, H., Callahan, M., Wolchok, J. D., Halaban, R., Dhodapkar, M. V., Dhodapkar, K. M.

Journal:

The Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

13

Immune Checkpoint Blockade in Cancer Therapy

Postow, M. A., Callahan, M. K., Wolchok, J. D.

Journal:

Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 474 KB

english, 2015

14

Five-Year Survival Rates for Treatment-Naive Patients With Advanced Melanoma Who Received Ipilimumab Plus Dacarbazine in a Phase III Trial

Maio, M., Grob, J.-J., Aamdal, S., Bondarenko, I., Robert, C., Thomas, L., Garbe, C., Chiarion-Sileni, V., Testori, A., Chen, T.-T., Tschaika, M., Wolchok, J. D.

Journal:

Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 122 KB

english, 2015

15

Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy

Zamarin, D., Holmgaard, R. B., Subudhi, S. K., Park, J. S., Mansour, M., Palese, P., Merghoub, T., Wolchok, J. D., Allison, J. P.

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

16

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma

Simpson, T. R., Li, F., Montalvo-Ortiz, W., Sepulveda, M. A., Bergerhoff, K., Arce, F., Roddie, C., Henry, J. Y., Yagita, H., Wolchok, J. D., Peggs, K. S., Ravetch, J. V., Allison, J. P., Quezada, S.

Journal:

Journal of Experimental Medicine

Year:

2013

Language:

english

File:

PDF, 4.68 MB

english, 2013

17

Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center

Horvat, T. Z., Adel, N. G., Dang, T.-O., Momtaz, P., Postow, M. A., Callahan, M. K., Carvajal, R. D., Dickson, M. A., D'Angelo, S. P., Woo, K. M., Panageas, K. S., Wolchok, J. D., Chapman, P. B.

Journal:

Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 212 KB

english, 2015

18

PD-1 Blockers

Wolchok, Jedd D.

Journal:

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

19

[ACM Press the 17th ACM conference - Chicago, Illinois, USA (2010.10.04-2010.10.08)] Proceedings of the 17th ACM conference on Computer and communications security - CCS '10 - Security analysis of India's electronic voting machines

Wolchok, Scott, Wustrow, Eric, Halderman, J. Alex, Prasad, Hari K., Kankipati, Arun, Sakhamuri, Sai Krishna, Yagati, Vasavya, Gonggrijp, Rop

Year:

2010

Language:

english

File:

PDF, 7.02 MB

english, 2010

20

Targeting cytotoxic T-lymphocyte antigen 4 in immunotherapies for melanoma and other cancers

Page, David B, Yuan, Jianda, Wolchok, Jedd D

Journal:

Year:

2010

Language:

english

File:

PDF, 2.73 MB

english, 2010

21

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

Sharma, M. D., Shinde, R., McGaha, T. L., Huang, L., Holmgaard, R. B., Wolchok, J. D., Mautino, M. R., Celis, E., Sharpe, A. H., Francisco, L. M., Powell, J. D., Yagita, H., Mellor, A. L., Blazar, B.

Journal:

Science Advances

Year:

2015

Language:

english

File:

PDF, 2.70 MB

english, 2015

22

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2016

Language:

english

File:

PDF, 646 KB

english, 2016

23

Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor

Belum, V.R., Benhuri, B., Postow, M.A., Hellmann, M.D., Lesokhin, A.M., Segal, N.H., Motzer, R.J., Wu, S., Busam, K.J., Wolchok, J.D., Lacouture, M.E.

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 2.16 MB

english, 2016

24

Patient-Physician Communication in the 21st Century

Friedman, Claire F., Wolchok, Jedd D.

Journal:

Trends in Immunology

Year:

2016

Language:

english

File:

PDF, 346 KB

english, 2016

25

Allografts for Ligamentous Reconstruction of the Knee

McGuire, David A., Wolchok, Jeffrey C.

Journal:

Techniques in Knee Surgery

Year:

2003

Language:

english

File:

PDF, 1.34 MB

english, 2003

26

Pitfalls and Tips for the Management of Injuries of the Anterior Cruciate Ligament

McGuire, David A., Hendricks, Stephen D., Wolchok, Jeffrey C.

Journal:

Techniques in Orthopaedics

Year:

1999

File:

PDF, 1.30 MB

1999

27

Potentiation of immunomodulatory antibody therapy with oncolytic viruses for treatment of cancer

Zamarin, Dmitriy, Wolchok, Jedd D

Journal:

Molecular Therapy — Oncolytics

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

28

Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications

Shia, Jinru, Schultz, Nikolaus, Kuk, Deborah, Vakiani, Efsevia, Middha, Sumit, Segal, Neil H, Hechtman, Jaclyn F, Berger, Michael F, Stadler, Zsofia K, Weiser, Martin R, Wolchok, Jedd D, Boland, C Ric

Journal:

Modern Pathology

Year:

2017

Language:

english

File:

PDF, 2.88 MB

english, 2017

29

Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies

Byun, David J., Wolchok, Jedd D., Rosenberg, Lynne M., Girotra, Monica

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2017

Language:

english

File:

PDF, 672 KB

english, 2017

30

Curbing Tregs’ (Lack of) Enthusiasm

Merghoub, Taha, Wolchok, Jedd D.

Journal:

Year:

2017

Language:

english

File:

PDF, 228 KB

english, 2017

31

Improved Survival and Intracranial Control Associated With Radiation Necrosis After Ipilimumab and Stereotactic Radiosurgery for Melanoma Brain Metastases

Wild, A., Kiess, A.P., Yang, T.J., Weg, E.S., Kohutek, Z.A., Wolchok, J.D., Postow, M.A., Tabar, V.S., Brennan, C.W., Chan, T.A., Yamada, Y., Beal, K.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2017

Language:

english

File:

PDF, 167 KB

english, 2017

32

Introduction by the Guest Editors

Wolchok, Jedd D., Callahan, Margaret K.

Journal:

The Cancer Journal

Year:

2018

Language:

english

File:

PDF, 48 KB

english, 2018

33

Introducing a New Series: Immunotherapy Facts and Hopes

Melero, Ignacio, Sznol, Mario, Tessmer, Marlowe S., Whiteside, Theresa L., Wolchok, Jedd D.

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 163 KB

english, 2018

34

Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials

Schadendorf, Dirk, Wolchok, Jedd D., Hodi, F. Stephen, Chiarion-Sileni, Vanna, Gonzalez, Rene, Rutkowski, Piotr, Grob, Jean-Jacques, Cowey, C. Lance, Lao, Christopher D., Chesney, Jason, Robert, Carol

Journal:

Journal of Clinical Oncology

Year:

2017

File:

PDF, 1005 KB

2017

35

Adjuvant ipilimumab versus placebo after complete resection of stage III melanoma: long-term follow-up results of the European Organisation for Research and Treatment of Cancer 18071 double-blind phase 3 randomised trial

Eggermont, Alexander M.M., Chiarion-Sileni, Vanna, Grob, Jean-Jacques, Dummer, Reinhard, Wolchok, Jedd D., Schmidt, Henrik, Hamid, Omid, Robert, Caroline, Ascierto, Paolo Antonio, Richards, Jon M., Le

Journal:

European Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

36

Quality of life for adult leukemia survivors treated on clinical trials of cancer and leukemia group B during the period 1971-1988 : Predictors for later psychologic distress

Donna B. Greenberg, Alice B. Kornblith, James E. Herndon, Enid Zuckerman, Charles A. Schiffer, Raymond B. Weiss, Robert J. Mayer, Silkaly M. Wolchok, Jimmie C. Holland

Journal:

Year:

1997

Language:

english

File:

PDF, 105 KB

english, 1997

37

Design and characterization of a modified T-flask bioreactor for continuous monitoring of engineered tissue stiffness

Richard A. Lasher, Jeffrey C. Wolchok, Monir K. Parikh, James P. Kennedy, Robert W. Hitchcock

Journal:

Biotechnology Progress

Year:

2010

Language:

english

File:

PDF, 1.46 MB

english, 2010

38

Temozolomide plus thalidomide in patients with brain metastases from melanoma : A Phase II study

Wen-Jen Hwu, Eric Lis, Jennifer H. Menell, Katherine S. Panageas, Lynne A. Lamb, Janene Merrell, Linda J. Williams, Susan E. Krown, Paul B. Chapman, Philip O. Livingston, Jedd D. Wolchok, Alan N. Houg

Journal:

Year:

2005

Language:

english

File:

PDF, 98 KB

english, 2005

39

Phase II study of temozolomide plus pegylated interferon-α-2b for metastatic melanoma

Wen-Jen Hwu, Katherine S. Panageas, Jennifer H. Menell, Lynne A. Lamb, Suzan Aird, Susan E. Krown, Linda J. Williams, Paul B. Chapman, Philip O. Livingston, Jedd D. Wolchok, Alan N. Houghton

Journal:

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

40

Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting : Lymphocyte count after 2 doses correlates with survival

Geoffrey Y. Ku, Jianda Yuan, David B. Page, Sebastian E. A. Schroeder, Katherine S. Panageas, Richard D. Carvajal, Paul B. Chapman, Gary K. Schwartz, James P. Allison, Jedd D. Wolchok

Journal:

Year:

2010

Language:

english

File:

PDF, 296 KB

english, 2010

41

Induction of autoantibodies to syngeneic prostate-specific membrane antigen by xenogeneic vaccination

Polly D. Gregor, Jedd D. Wolchok, Vandana Turaga, Jean-Baptiste Latouche, Michel Sadelain, Dean Bacich, Warren D.W. Heston, Alan N. Houghton, Howard I. Scher

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

42

The isolation of cell derived extracellular matrix constructs using sacrificial open-cell foams

Jeffrey C. Wolchok, Patrick A. Tresco

Journal:

Year:

2010

Language:

english

File:

PDF, 2.18 MB

english, 2010

43

Post-operative Radiotherapy after Complete Surgical Resection for Head and Neck Mucosal Melanoma

A.J. Wu, J. Gomez, J. Zhung, K. Chan, D. Gomez, S. Wolden, M.J. Zelefsky, J. Wolchok, R. Wong, N.Y. Lee

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 37 KB

english, 2008

44

The effect of intersegmental knee moments on patellofemoral contact mechanics in cycling

Jeffrey C Wolchok, M.L Hull, Stephen M Howell

Journal:

Journal of Biomechanics

Year:

1998

Language:

english

File:

PDF, 247 KB

english, 1998

45

Multiple pathways to tumor immunity and concomitant autoimmunity

Mary Jo Turk, Jedd D. Wolchok, José A. Guevara-Patino, Stacie M. Goldberg, Alan N. Houghton

Journal:

Immunological Reviews

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

46

WT1 peptide vaccinations induce CD4 and CD8 T cell immune responses in patients with mesothelioma and non-small cell lung cancer

Lee M. Krug, Tao Dao, Andrew B. Brown, Peter Maslak, William Travis, Sara Bekele, Tatyana Korontsvit, Victoria Zakhaleva, Jedd Wolchok, Jianda Yuan, Hao Li, Leslie Tyson, David A. Scheinberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

47

The effect of bioreactor induced vibrational stimulation on extracellular matrix production from human derived fibroblasts

Jeffrey C. Wolchok, Chad Brokopp, Clayton J. Underwood, Patrick A. Tresco

Journal:

Year:

2009

Language:

english

File:

PDF, 692 KB

english, 2009

48

Dual Mode Reflectance and Fluorescence Confocal Laser Scanning Microscopy for In Vivo Imaging Melanoma Progression in Murine Skin

Li, Yanyun, Gonzalez, Salvador, Terwey, Theis H, Wolchok, Jedd, Li, Yongbiao, Aranda, Iana, Toledo-Crow, Ricardo, Halpern, Allan C

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 3.87 MB

english, 2005

49

Diffuse melanosis after chemotherapy-induced tumor lysis syndrome in a patient with metastatic melanoma

Klaus J. Busam, Jedd Wolchok, Achim A. Jungbluth, Paul Chapman

Journal:

Journal of Cutaneous Pathology

Year:

2004

Language:

english

File:

PDF, 2.32 MB

english, 2004

50

Xenogeneic Human Tyrosinase DNA Vaccination Induces Specific Immune Response in Dogs with Advanced Malignant Melanoma

J. Liao, P. Gregor, F. Orlandi, D. M. Craft, C. Leung, A. N. Houghton, J. D. Wolchok, P. J. Bergman

Journal:

Veterinary and Comparative Oncology

Year:

2005

Language:

english

File:

PDF, 196 KB

english, 2005